Larbert Railway Station, like many, was once more significant than it is today. It opened in 1848 beneath a bridge which carries Main Street over the new Scottish Central Railway, and comprised two platforms and several sidings. The railway was eventually to bring the Falkirk Cattle Trysts to an end, allowing beasts to be brought to the towns and cities of the central belt much more easily than had been possible before. These trysts had been held to the east of Larbert from 1785.
A plaque in the station commemorates the 215 officers and men of the Royal Scots killed in the Quintinshill Rail Disaster of 1915, who boarded the troop train at Larbert which carried them to their deaths.
The station benefitted from a £850,000 facelift in 2007 and a £4 million training centre was opened here by Network Rail in 2008. This is the principal training facility for railway maintenance staff in Scotland and includes more than 200m (656 feet) of track and signals for demonstration purposes.