Duffus is a coastal parish, which lies in Moray Council Area, some 5 miles (8 km) northwest of Elgin and 9 miles (14 km) northeast of Forres in Moray.
It is located in the old county of Moray, which disappeared following the Local Government (Scotland) Act 1974.
The parish has an area of 38.6 sq. km (14.9 sq. miles). Duffus has Alves, Drainie and Spynie as its neighbouring parishes. The boundaries of this parish were modified among significant changes recommended by the Boundary Commissioners after the Local Government (Scotland) Act 1889.