Dumfries and Galloway Royal Infirmary is a 344-bed general hospital which opened in 2017 on a greenfield site at Cargenbridge, 2 miles (3 km) west southwest of the centre of Dumfries. This site is easily accessible from the A75 Trunk Road which cuts across the region. Designed by Ryder Architecture under a Private Finance Initiative (PFI) contract, the £212-million building is designed around 'garden hospital' principles, with the landscaping incorporating pre-existing natural features. The building makes use of contrasting white-granite and honey-blonde sandstone mix reconstituted pre-cast stone panels, and comprises pavilions built around seventeen courtyards with gardens.
The hospital offers a full range of specialisms, including obstetrics and gynaecology, maternity, paediatrics, cardiology, neurology, stroke, cancer-care and geriatric medicine. It provides the principal accident and emergency service for South West Scotland, together with general surgery, ear, nose and throat surgery, orthopaedic surgery and a day-surgery unit.
The former infirmary was located on Bankend Road, a mile (1.5 km) south southeast of the centre of Dumfries and opened by HM Queen Elizabeth II in 1975. Part of this is now serves a day hospital, known as the Mountainhall Treatment Centre, providing audiology, ophthalmology, renal dialysis and diabetic services. An older infirmary on Nith Bank is a fine Italianate building dating from 1872, which now comprises an office for Dumfries and Galloway Health Board. The first Dumfries hospital opened in Burns Street in 1776.